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事件日期	中文股东名称	持股人名字	涉及股份(股)	先前结余(股)	先前结余率(%)	先前类别	目前结余(股)	目前结余率(%)	目前类别	股份类别
2024-09-04	Easy Sonic International Limited	Easy Sonic International Limited	211151750	211151750	0.2667	L	0	0.0000	L	普通股
2024-09-04	Vistra Trust (Singapore) Pte. Limited	Vistra Trust (Singapore) Pte. Limited	211151750	211151750	0.2667	L	0	0.0000	L	普通股
2024-09-04	Vistra Trust (Singapore) Pte. Limited	Vistra Trust (Singapore) Pte. Limited	211151750	211151750	0.2667	L	0	0.0000	L	普通股
2024-09-04	Silver Summit Group Limited	Silver Summit Group Limited	211151750	211151750	0.2667	L	0	0.0000	L	普通股
2024-01-26	沈竹	沈竹	10000000	221151750	0.2793	L	211151750	0.2667	L	普通股
2024-01-26	Willgenpharma Ltd	Willgenpharma Ltd	10000000	221151750	0.2793	L	211151750	0.2667	L	普通股
2024-01-26	Yakovpharma Ltd	Yakovpharma Ltd	10000000	221151750	0.2793	L	211151750	0.2667	L	普通股
2024-01-26	Johwpharma Ltd	Johwpharma Ltd	10000000	221151750	0.2793	L	211151750	0.2667	L	普通股
2024-01-26	Honourpharma Ltd	Honourpharma Ltd	10000000	221151750	0.2793	L	211151750	0.2667	L	普通股
2024-01-26	胡云雁	胡云雁	10000000	221151750	0.2793	L	211151750	0.2667	L	普通股
2024-01-26	王印祥	王印祥	10000000	221151750	0.2793	L	211151750	0.2667	L	普通股
2024-01-26	王晓洁	王晓洁	10000000	221151750	0.2793	L	211151750	0.2667	L	普通股
2024-01-26	ULTIMATE ESTATE LIMITED	ULTIMATE ESTATE LIMITED	10000000	221151750	0.2793	L	211151750	0.2667	L	普通股
2024-01-26	TREASURE PARTNER INTERNATIONAL LIMITED	TREASURE PARTNER INTERNATIONAL LIMITED	10000000	221151750	0.2793	L	211151750	0.2667	L	普通股
2024-01-26	Hmed Ltd	Hmed Ltd	0	221151750	0.2793	L	211151750	0.2667	L	普通股
2024-01-26	Blesspharma Ltd	Blesspharma Ltd	10000000	221151750	0.2793	L	211151750	0.2667	L	普通股
2024-01-26	Gloryviewpharma Ltd	Gloryviewpharma Ltd	10000000	221151750	0.2793	L	211151750	0.2667	L	普通股
2024-01-26	Risepharma Ltd	Risepharma Ltd	10000000	221151750	0.2793	L	211151750	0.2667	L	普通股
2023-04-14	Center Laboratories, Inc.	Center Laboratories, Inc.	8120400	95607290	0.1205	L	87486890	0.1102	L	普通股
2023-04-14	Center Venture Holding I Limited (formerly known as BioEngine Capital Holding Limited)	Center Venture Holding I Limited (formerly known as BioEngine Capital Holding Limited)	8120400	87557000	0.1103	L	79436600	0.1001	L	普通股
2023-02-17	胡云雁	胡云雁	22100100	198383550	0.2572	L	220483650	0.2778	L	普通股
2023-02-17	王晓洁	王晓洁	22100100	198383550	0.2572	L	220483650	0.2778	L	普通股
2023-02-17	王印祥	王印祥	22100100	198383550	0.2572	L	220483650	0.2778	L	普通股
2023-02-17	Yakovpharma Ltd	Yakovpharma Ltd	22100100	198383550	0.2572	L	220483650	0.2778	L	普通股
2023-02-17	Willgenpharma Ltd	Willgenpharma Ltd	22100100	198383550	0.2572	L	220483650	0.2778	L	普通股
2023-02-17	TREASURE PARTNER INTERNATIONAL LIMITED	TREASURE PARTNER INTERNATIONAL LIMITED	22100100	198383550	0.2572	L	220483650	0.2778	L	普通股
2023-02-17	ULTIMATE ESTATE LIMITED	ULTIMATE ESTATE LIMITED	22100100	198383550	0.2572	L	220483650	0.2778	L	普通股
2023-02-17	Risepharma Ltd	Risepharma Ltd	22100100	198383550	0.2572	L	220483650	0.2778	L	普通股
2023-02-17	Johwpharma Ltd	Johwpharma Ltd	22100100	198383550	0.2572	L	220483650	0.2778	L	普通股
2023-02-17	Honourpharma Ltd	Honourpharma Ltd	22100100	198383550	0.2572	L	220483650	0.2778	L	普通股
2023-02-17	Hmed Ltd	Hmed Ltd	22100100	198383550	0.2572	L	220483650	0.2778	L	普通股
2023-02-17	Gloryviewpharma Ltd	Gloryviewpharma Ltd	22100100	198383550	0.2572	L	220483650	0.2778	L	普通股
2023-02-17	Blesspharma Ltd	Blesspharma Ltd	22100100	198383550	0.2572	L	220483650	0.2778	L	普通股
2023-02-10	胡云雁	胡云雁	22100100	220483650	0.2858	L	198383550	0.2572	L	普通股
2023-02-10	王印祥	王印祥	22100100	220483650	0.2858	L	198383550	0.2572	L	Ordinary Shares
2023-02-10	王晓洁	王晓洁	22100100	220483650	0.2858	L	198383550	0.2572	L	普通股
2023-02-10	Yakovpharma Ltd	Yakovpharma Ltd	22100100	220483650	0.2858	L	198383550	0.2572	L	普通股
2023-02-10	Willgenpharma Ltd	Willgenpharma Ltd	22100100	220483650	0.2858	L	198383550	0.2572	L	普通股
2023-02-10	TREASURE PARTNER INTERNATIONAL LIMITED	TREASURE PARTNER INTERNATIONAL LIMITED	22100100	220483650	0.2858	L	198383550	0.2572	L	普通股
2023-02-10	ULTIMATE ESTATE LIMITED	ULTIMATE ESTATE LIMITED	22100100	220483650	0.2858	L	198383550	0.2572	L	普通股
2023-02-10	Risepharma Ltd	Risepharma Ltd	22100100	220483650	0.2858	L	198383550	0.2572	L	普通股
2023-02-10	Johwpharma Ltd	Johwpharma Ltd	22100100	220483650	0.2858	L	198383550	0.2572	L	普通股
2023-02-10	Honourpharma Ltd	Honourpharma Ltd	22100100	220483650	0.2858	L	198383550	0.2572	L	普通股
2023-02-10	Hmed Ltd	Hmed Ltd	22100100	220483650	0.2858	L	198383550	0.2572	L	普通股
2023-02-10	Gloryviewpharma Ltd	Gloryviewpharma Ltd	22100100	220483650	0.2858	L	198383550	0.2572	L	普通股
2023-02-10	Blesspharma Ltd	Blesspharma Ltd	22100100	220483650	0.2858	L	198383550	0.2572	L	普通股
2022-08-02	BioEngine Capital Inc. (dissolved)	BioEngine Capital Inc. (dissolved)	0	87557000	0.1135	L	0	0.0000	L	普通股
2022-05-18	LAV Asset Management (Hong Kong) Limited	LAV Asset Management (Hong Kong) Limited	60734925	0	0.0000	L	60734925	0.0787	L	普通股
2022-03-22	胡邵京	胡邵京	229960475	271250475	0.3516	L	41290000	0.0535	L	普通股
2022-03-22	Willgenpharma Ltd	Willgenpharma Ltd	41290000	271250475	0.3516	L	229960475	0.2981	L	普通股
2022-03-22	Yakovpharma Ltd	Yakovpharma Ltd	41290000	271250475	0.3516	L	229960475	0.2981	L	普通股
2022-03-22	Johwpharma Ltd	Johwpharma Ltd	41290000	271250475	0.3516	L	229960475	0.2981	L	普通股
2022-03-22	Honourpharma Ltd	Honourpharma Ltd	41290000	271250475	0.3516	L	229960475	0.2981	L	普通股
2022-03-22	Risepharma Ltd	Risepharma Ltd	41290000	271250475	0.3516	L	229960475	0.2981	L	普通股
2022-03-22	Gloryviewpharma Ltd	Gloryviewpharma Ltd	41290000	271250475	0.3516	L	229960475	0.2981	L	普通股
2022-03-22	Blesspharma Ltd	Blesspharma Ltd	41290000	271250475	0.3516	L	229960475	0.2981	L	普通股
2022-03-22	Emmanuelhupharma Ltd	Emmanuelhupharma Ltd	229960475	271250475	0.3516	L	41290000	0.0535	L	普通股
2022-03-22	Hmed Ltd	Hmed Ltd	41290000	271250475	0.3516	L	229960475	0.2981	L	普通股
2022-03-22	王印祥	王印祥	41290000	271250475	0.3516	L	229960475	0.2981	L	普通股
2022-03-22	王晓洁	王晓洁	41290000	271250475	0.3516	L	229960475	0.2981	L	普通股
2022-03-22	胡邵京	胡邵京	229960475	271250475	0.3516	L	41290000	0.0535	L	普通股
2022-03-22	胡云雁	胡云雁	41290000	271250475	0.3516	L	229960475	0.2981	L	普通股
2022-03-22	王印祥	王印祥	41290000	271250475	0.3516	L	229960475	0.2981	L	普通股
2021-07-14	BioEngine Capital Inc.	BioEngine Capital Inc.	10779000	98330000	0.1275	L	87557000	0.1135	L	普通股
2021-07-14	BioEngine Capital Holding Limited	BioEngine Capital Holding Limited	10779000	98330000	0.1275	L	87557000	0.1135	L	普通股
2021-07-14	Center Laboratories Inc.	Center Laboratories Inc.	0	118818890	0.1540	L	98508890	0.1280	L	普通股
2020-12-31	Rieschel Gary Edward	Rieschel Gary Edward	0	81825555	0.1077	L	0	0.0000	L	普通股
2020-12-31	梁颕宇	梁颕宇	0	81825555	0.1077	L	0	0.0000	L	普通股
2020-12-31	邝子平	邝子平	0	81825555	0.1077	L	0	0.0000	L	普通股
2020-12-21	Hillhouse Capital Management, Ltd.	Hillhouse Capital Management, Ltd.	0	0	0.0000	L	56861110	0.0749	L	普通股
2020-12-21	Hillhouse Fund IV, L.P.	Hillhouse Fund IV, L.P.	0	0	0.0000	L	56861110	0.0749	L	普通股
2020-12-21	HH SPR-III Holdings Limited	HH SPR-III Holdings Limited	0	0	0.0000	L	56861110	0.0749	L	普通股
2020-12-21	BioEngine Capital Inc.	BioEngine Capital Inc.	0	0	0.0000	L	98330000	0.1294	L	普通股
2020-12-21	BioEngine Capital Holding Limited	BioEngine Capital Holding Limited	0	0	0.0000	L	98330000	0.1294	L	普通股
2020-12-21	Center Laboratories Inc.	Center Laboratories Inc.	0	0	0.0000	L	118818890	0.1564	L	普通股
2020-12-21	梁頴宇	梁頴宇	81825555	0	0.0000	L	81825555	0.1077	L	普通股
2020-12-21	Rieschel Gary Edward	Rieschel Gary Edward	81825555	0	0.0000	L	81825555	0.1077	L	普通股
2020-12-21	邝子平	邝子平	81825555	0	0.0000	L	81825555	0.1077	L	普通股
2020-12-21	Qiming Corporate GP VI, Ltd	Qiming Corporate GP VI, Ltd	49605555	0	0.0000	L	49605555	0.0653	L	普通股
2020-12-21	Qiming GP VI, L.P.	Qiming GP VI, L.P.	48305740	0	0.0000	L	48305740	0.0636	L	普通股
2020-12-21	Qiming Venture Partners VI, L.P.	Qiming Venture Partners VI, L.P.	48305740	0	0.0000	L	48305740	0.0636	L	普通股
2020-12-21	LAV Corporate IV GP, Ltd.	LAV Corporate IV GP, Ltd.	47670875	0	0.0000	L	47670875	0.0628	L	普通股
2020-12-21	LAV GP IV, L.P.	LAV GP IV, L.P.	47670875	0	0.0000	L	47670875	0.0628	L	普通股
2020-12-21	LAV Biosciences Fund IV, L.P.	LAV Biosciences Fund IV, L.P.	47670875	0	0.0000	L	47670875	0.0628	L	普通股
2020-12-21	LAV Coda Limited	LAV Coda Limited	42134075	0	0.0000	L	42134075	0.0555	L	普通股
2020-12-21	施毅	施毅	59587425	0	0.0000	L	59587425	0.0784	L	普通股
2020-12-21	LAV Biosciences Fund IV, L.P.	LAV Biosciences Fund IV, L.P.	47670875	0	0.0000	L	47670875	0.0628	L	普通股
2020-12-21	LAV Corporate IV GP, Ltd.	LAV Corporate IV GP, Ltd.	47670875	0	0.0000	L	47670875	0.0628	L	普通股
2020-12-21	LAV GP IV, L.P.	LAV GP IV, L.P.	47670875	0	0.0000	L	47670875	0.0628	L	普通股
2020-12-21	LAV Coda Limited	LAV Coda Limited	47670875	0	0.0000	L	47670875	0.0628	L	普通股
2020-12-21	施毅	施毅	59587425	0	0.0000	L	59587425	0.0784	L	普通股

回购日期	回购数量(股)	最高回购价(港元)	最低回购价(港元)	回购总价(港元)	平均回购价(港元)
2024-10-25	188400	1.9700	1.9400	367518.0000	1.951
2024-10-21	65400	1.9000	1.8700	123402.0000	1.887
2024-10-18	119700	1.9100	1.8200	224427.0000	1.875
2024-10-09	124800	1.8900	1.7500	227907.0000	1.826
2024-10-08	100200	2.0300	1.8800	197232.0000	1.968
2024-06-27	163500	1.5300	1.5100	250593.0000	1.533
2024-06-26	139500	1.6300	1.5800	223026.0000	1.599
2024-06-25	155400	1.6100	1.5800	248571.0000	1.600
2024-06-24	160500	1.6200	1.5800	256422.0000	1.598
2024-06-21	231300	1.6400	1.6000	374340.0000	1.618
2024-06-20	276300	1.6400	1.6100	449778.0000	1.628
2024-06-19	294000	1.6400	1.6200	479379.0000	1.631
2024-06-18	226800	1.6500	1.6100	369429.0000	1.629
2024-06-17	430200	1.7000	1.6400	720195.0000	1.674
2024-06-14	203700	1.8600	1.8400	377553.0000	1.853
2024-06-13	54000	1.8500	1.8400	99756.0000	1.847
2023-09-29	1011300	3.2000	3.0600	3197406.0000	3.162
2023-09-26	156300	3.2400	3.1500	494058.0000	3.161
2023-08-31	499800	3.8400	3.7300	1899402.0000	3.800
2023-07-25	9900	4.1300	4.1000	40698.0000	4.111
2023-07-24	129900	3.7800	3.7200	489546.0000	3.769