ANNOUNCEMENT PURSUANT TO RULE 3.8 OF THE TAKEOVERS CODE

Hong Kong Exchanges and Clearing Limited and The Stock Exchange of Hong Kong Limited take no responsibility for the contents of this announcement make no representation as to its accuracy or completeness and expressly disclaim any liability whatsoever for any loss howsoever arising from or in reliance upon the whole or any part of the contents of this announcement.This announcement appears for information purposes only and does not constitute an invitation or offer to acquire purchase or subscribe for securities of the Offeror or the Company nor is it a solicitation of any vote or approval in any jurisdiction.This announcement is not for release publication or distribution in whole or in part in into or from any jurisdiction where to do so would constitute a violation of the applicable laws or regulations of such jurisdiction.SciClone Pharmaceuticals (Holdings) Limited 赛生药业控股有限公司* (Incorporated in the Cayman Islands with limited liability) (Stock Code: 6600) ANNOUNCEMENT PURSUANT TO RULE 3.8 OF THE TAKEOVERS CODE This announcement is made by SciClone Pharmaceuticals (Holdings) Limited (the “Company”) pursuant to Rule 3.8 of The Hong Kong Code on Takeovers and Mergers (the “Takeovers Code”).Reference is made to (i) the joint announcement issued by Silver Pegasus Investment Limited (the “Offeror”) and the Company dated 28 March 2024 (the “Joint Announcement”) in respect of among other things the proposal for the privatisation of the Company by the Offeror by way of a scheme of arrangement under section 86 of the Companies Act; (ii) the composite scheme document issued by the Offeror and the Company dated 23 May 2024; (iii) the option incentive plan approved and adopted by the Company on 24 June 2018 (the “Option Incentive Plan”); (iv) the post-IPO share option scheme adopted by Shareholders’ resolution on 22 January 2021 (the “Post-IPO Option Plan”); and (v) the announcements of the Company pursuant to Rule 3.8 of the Takeovers Code published on 1 April 2024 2 April 2024 3 April 2024 8 April 2024 12 April 2024 15 April 2024 17 April 2024 18 April 2024 19 April 2024 22 April 2024 23 April 2024 26 April 2024 30 April 2024 6 May 2024 7 May 2024 8 May 2024 10 May 2024 13 May 2024 14 May 2024 16 May 2024 17 May 2024 20 May 2024 22 May 2024 23 May 2024 24 May 2024 27 May 2024 28 May 2024 29 May 2024 30 May 2024 31 May 2024 3 June 2024 4 June 2024 5 June 2024 and 7 June 2024. Unless otherwise defined herein capitalized terms used herein shall have the same meanings as those defined in the Joint Announcement.– 1 –UPDATE ON THE NUMBER OF RELEVANT SECURITIES OF THE COMPANY The Board announces that on 15 June 2024 12500 Share Options granted under the Post-IPO Option Plan had lapsed pursuant to the rules of the Post-IPO Option Plan.Details of all classes of relevant securities (as defined in Note 4 to Rule 22 of the Takeovers Code) issued by the Company and the numbers of such securities in issue and outstanding as at the date of this announcement are as follows: (a) a total of 630543012 Shares in issue; and (b) immediately following the lapse of Share Options as set out above a total of 66218552 Share Options in issue (comprising (i) a total of 16337000 Share Options (all of which are vested) entitling the holders to receive 16337000 existing Shares from the Option Trustee under the Option Incentive Plan; (ii) a total of 19844842 Share Options (all of which are vested) entitling the holders to subscribe for 19844842 new Shares under the Option Incentive Plan; and (iii) a total of 30036710 Share Options (21042910 of which are vested) entitling the holders to subscribe for 30036710 new Shares under the Post-IPO Option Plan). As at the date of this announcement save as disclosed above the Company has no outstanding securities options derivatives or warrants which are convertible or exchangeable into Shares and the Company has no other relevant securities (as defined in Note 4 to Rule 22 of the Takeovers Code).– 2 –DEALING DISCLOSURE The respective associates (as defined in Note 4 to Rule 22 of the Takeovers Code) of the Company and the Offeror are hereby reminded to disclose their dealings in the relevant securities (as defined in Note 4 to Rule 22 of the Takeovers Code) of the Company under Rule 22 of the Takeovers Code during the offer period.In accordance with Rule 3.8 of the Takeovers Code reproduced below is the full text of Note 11 to Rule 22 of the Takeovers Code:“Responsibilities of stockbrokers banks and other intermediariesStockbrokers banks and others who deal in relevant securities on behalf of clients have a general duty to ensure so far as they are able that those clients are aware of the disclosure obligations attaching to associates of an offeror or the offeree company and other persons under Rule 22 and that those clients are willing to comply with them. Principal traders and dealers who deal directly with investors should in appropriate cases likewise draw attention to the relevant Rules. However this does not apply when the total value of dealings (excluding stamp duty and commission) in any relevant security undertaken for a client during any 7 day period is less than $1 million.This dispensation does not alter the obligation of principals associates and other persons themselves to initiate disclosure of their own dealings whatever total value is involved.Intermediaries are expected to co-operate with the Executive in its dealings enquiries.Therefore those who deal in relevant securities should appreciate that stockbrokers and other intermediaries will supply the Executive with relevant information as to thosedealings including identities of clients as part of that co-operation.” – 3 –WARNINGS Shareholders and potential investors should be aware that the implementation of the Proposal the Scheme and the Option Offer is subject to the Conditions being fulfilled or waived (including the approval of the Rollover Arrangements as a special deal under Rule 25 of the Takeovers Code) as applicable and thus the Proposal may or may not be implemented the Scheme may or may not become effective and the Option Offer may or may not be implemented. Shareholders and potential investors should therefore exercise caution when dealing in the securities of the Company. Persons who are in doubt as to the action they should take should consult their stockbroker bank manager solicitor or other professional advisers.By order of the Board SciClone Pharmaceuticals (Holdings) Limited ZHAO Hong Executive Director Chief Executive Officer and President Hong Kong 16 June 2024 As at the date of this announcement the Board comprises Mr. Zhao Hong and Ms. Pan Rongrong as executive directors Mr. Li Zhenfu Dr. Daniel Luzius Vasella Ms. Lin Shirley Yi-Hsien and Ms. Wang Haixia as non-executive directors and Dr. Liu Guoen Dr. Chen Ping Mr. Gu Alex Yushao and Ms. Wendy Hayes as independent non-executive directors.The Directors jointly and severally accept full responsibility for accuracy of the information contained in this announcement and confirm having made all reasonable enquiries that to the best of their knowledge opinions expressed in this announcement by the Directors have been arrived at after due and careful consideration and there are no other facts not contained in this announcement the omission of which would make any statement in this announcement misleading.* for identification purpose only –4–